Diversions were in place on State Highway 1, between Washdyke and Kennels Rd, after two crashes on Saturday afternoon.
Three people received minor injuries after four vehicles were involved in two related incidents, near Washdyke, on Saturday.
Police Sergeant Sam Bellett, of Timaru, said the first incident occurred at 1.59pm when a driver failed to see a car turning from State Highway 1 into Kennels Rd, and the two vehicles collided.
Shortly after, a vehicle was being driven slowly by a motorist driving past the crash scene, and a car following failed to brake in time and drove into the back of it.
Bellett said the road was closed and detours were in place while the vehicles were removed.
St John said three people with minor injuries were treated at the scene, with one taken to Timaru Hospital.